导师姓名：周玉
出生年月：1969.01
职称职务：教授
最高学位：博士研究生
研究方向：食品安全
招生方向：食品科学与工程
办公电话：
电子邮箱：zhouyurunye@sina.com
个人简介：
周玉，男，1969年1月生。博士研究生学历，教授职称，硕（博）士生导师。
学习经历：
2002.09-2005.06，吉林大学畜牧兽医学院，攻读博士
1996.09-2000.07，军需大学基础部，攻读硕士
1989.09-1993.07，华中农业大学水产学院，攻读学士
工作履历：
(1) 2025.01-今 四川轻化工大学，生物工程学院，教授/博导
(2) 2019.11-2024.12, 长江大学, 动物科学技术学院, 教授/博导
(3) 2009.09-2019.10, 吉林大学, 人兽共患病研究所, 教授/博导
(4) 2004.07-2009.09, 吉林大学, 人兽共患病研究所, 副教授
(5) 1999.07-2004.07, 解放军军需大学, 畜牧兽医学院, 讲师
(6) 1993.07-1999.07, 解放军农牧大学, 畜牧水产系, 助教
学术兼职：
（1）国家食品药品监督管理局首批食品安全专家
（2）Biosensors & Bioelectronics等十余家SCI期刊审稿人；
（3）国家自然科学基金项目函评评审专家；
（4）ERA-Chemistry项目评审专家；
（5）国家重点研发计划重点专项、“政府间港澳台”重点专项、政府间重点专项、“农业农村部”重点专项等评审专家。
（6）“我要测网络讲堂-公益讲座”主讲专家。
（7）教育部学位中心，博士、硕士答辩前学位论文评审专家。
北京市、山东省、河北省、湖南省、内蒙古自治区、宁夏回族自治区、江苏省等科技奖励评审专家。
研究领域及主要成果：
食品和水环境中有害分子（重金属、中毒性生物毒素、多环芳烃及农兽药残留等）的高通量、高灵敏、快速检测新技术及手足口（EV71）、旋毛虫血清抗体及癌症生物标志物的高灵敏精准诊断新方法。
获得全国商业科技进步奖一等奖1项（第一署名）。发表研究论文200余篇，其中在Trend. Anal. Chem. (IF=13.1)、Biosen. Bioelectron.（IF = 12.6）、Sens. Actuators, B（IF = 9.2）、Food Chem.（IF = 8.8）和Anal. Chem.（IF=7.4）等国际权威SCI期刊以第一作者和/通信作者发表SCI论文80余篇（中科院一区有42篇，影响因子10.0以上的有11篇）。
主讲课程及教学改革：
仪器分析与实验设计（硕士）
食品安全专题（博士）
代表论文：
近5年（2020年以来）以第一作者/通讯作者身份发表论文目录（中科院一区22篇、二区24篇）：
[1] Yingli Guo, Xingping Zhang, Hualin Yang, Yu Zhou. Triple-readout immunoassay based on copper ion trigger for the detection of ochratoxin A. Analytica Chimica Acta 1345 (2025) 343750. 中科院一区
[2] Xin Yang, Yuanyuan Wang, Xiaowei Chen, Yujun Feng, Yingli Guo, Hualin Yang, Yu Zhou. Dual-mode detection of Ochratoxin A based on silver nanocluster and phosphate. Food Chemistry 474 (2025) 143131. 中科院一区
[3] Xiaowei Chen, Yujun Feng, Yuanyuan Wang, Xin Yang, Xingping Zhang, Hualin Yang, Yu Zhou. Colorimetric and fluorescence dual-mode detection of Oxytetracycline based on Hemin/G-quadruplex DNAzyme and ZIF-8. Food Control 168 (2025) 110942. 中科院一区
[4] Yuanyuan Wang, Xin Yang, Xiaowei Chen, Yujun Feng, Yingli Guo, Yu Zhou, Hualin Yang. Manganese dioxide nanosheets triggered fluorescence and colorimetric dual-mode immunoassay for detection of Ochratoxin A. Food Control 170 (2025) 111045. 中科院一区
[5] Yonghong Zha, Yansong Li, Jianhua Zhou, Xiaolan Liu, Ki Soo Park, Yu Zhou. Dual-Mode Fluorescent/Intelligent Lateral Flow Immunoassay Based on Machine Learning Algorithm for Ultrasensitive Analysis of Chloroacetamide Herbicides. Anal. Chem. 2024, 96, 12197−12204.中科院一区
[6] Yanan Zhao, Wang Chen, Huajuan Fang, Junxiang Zhang, Shixiang Wu, Hualin Yang, Yu Zhou. Ratiometric fluorescence immunoassay based on silver nanoclusters and calcein-Ce3+ for detecting ochratoxin A. Talanta, 269 (2024) 125470. 中科院一区
[7] Die Xu, Junxiang Zhang, Zhenzhen Luo, Yanan Zhao, Yuanhua Zhu, Hualin Yang, Yu Zhou. Ratiometric fluorescence and absorbance dual-model immunoassay based on 2,3-diaminophenazine and carbon dots for detecting Aflatoxin B1. Food Chemistry 439 (2024) 138125. 中科院一区
[8] Liyuan Ma, Xingping Zhang, Yao Xiao, Huajuan Fang, Guohao Zhang, Hualin Yang, Yu Zhou. Fluorescence and colorimetric dual-mode immunoassay based on G-quadruplex/N-methylmesoporphyrin IX and p-nitrophenol for detection of zearalenone. Food Chem., 401 (2023) 134190. 中科院一区
[9] Ning Xu, Yan Liu, Yansong Li, Bin Tang, Chen Li, Mingyuan Liu, Yu Zhou, Xiaolei Liu. Dual-functional AuNP-triggered hybridization chain reaction for enhanced competitive immunosensing for Trichinella spiralis antibody in zoonosis screening. Sens. Actuators B, 379 (2023)133300. 中科院一区
[10] Shixiang Wu, Xingping Zhang, Wang Chen, Guohao Zhang, Qian Zhang, Hualin Yang, Yu Zhou. Alkaline phosphatase triggered ratiometric fluorescence immunoassay for detection of zearalenone. Food Control, 146 (2023) 109541. 中科院一区
[11] Yao Yu; Yansong Li; Qi Zhang; Yonghong Zha; Shiying Lu; Yong Yang; Peiwu Li; Yu Zhou. Colorimetric immunoassay via smartphone based on Mn2+-mediated aggregation of AuNPs for convenient detection of FB. Food Control, 132 (2022) 108481. 中科院一区
[12] Wang Chen, Xingping Zhang, Qian Zhang, Guohao Zhang, Shixiang Wu, Hualin Yang, Yu Zhou. Cerium ions triggered dual-readout immunoassay based on aggregation induced emission effect and 3,3′,5,5′-tetramethylbenzidine for fluorescent and colorimetric detection of ochratoxin A. Anal. Chim. Acta, 1231 (2022) 340445. 中科院一区
[13] Cuiling Shang; Yansong Li; Qi Zhang; Song Tang; Xiaoqian Tang; Honglin Ren; Pan Hu; Shiying Lu; Peiwu Li; Yu Zhou. Alkaline phosphatase-triggered dual-signal immunoassay for colorimetric and electrochemical detection of zearalenone in cornmeal. Sens. Actuators B, 358 (2022) 131525. 中科院一区
[14] Yonghong Zha; Yansong Li; Pan Hu; Shiying Lu; Honglin Ren; Zengshan Liu; Hualin Yang; Yu Zhou. Duplex-specific nuclease-triggered fluorescence immunoassay based on dual-functionalized AuNP for acetochlor, metolachlor, and propisochlor. Anal. Chem., 2021, 93, 13886−13892. 中科院一区
[15] Naiyu Guan; Yansong Li; Hualin Yang; Pan Hu; Shiying Lu; Honglin Ren; Zengshan Liu; Ki Soo Park; Yu Zhou. Dual-functionalized gold nanoparticles probe based bio-barcode immuno-PCR for the detection of glyphosate. Food Chem., 338 (2021) 128133. 中科院一区
[16] Taehwi Yoon; Seokjoon Kim; Jiye Shin; Yu Zhou; Ki Soo Park, Highly sensitive multiplex detection of microRNA using light-up RNA aptamers. Sens. Actuators B, 330 (2021) 129410. 中科院一区
[17] Yan Liu; Ning Xu; Yansong Li; Bin Tang; Hualin Yang; Weihua Gao; Mingyuan Liu; Xiaolei Liu; Yu Zhou. Recombinant cystatin-like protein-based competition ELISA for Trichinella spiralis antibody test in multihost sera. PloS Neglect. Trop. D., 2021, 8: 1834. 中科院一区
[18] Yonghong Zha; Shiying Lu; Pan Hu; Honglin Ren; Zengshan Liu; Weihua Gao; Chengmin Zhao; Yansong Li; Yu Zhou. Dual-modal Immunosensor with Functionalized Gold Nanoparticles for Ultrasensitive Detection of Chloroacetamide Herbicides. ACS Appl. Mater. Interfaces, 2021, 13, 6091−6098. 中科院一区
[19] Hualin Yang; Yu Zhou; Juewen Liu. Porphyrin metalation catalyzed by DNAzymes and nanozymes. Inorg. Chem. Front., 2021, 8, 2183-2199. 中科院一区
[20] Hualin Yang; Yu Zhou; Juewen Liu. G-quadruplex DNA for construction of biosensors. Trends Anal. Chem., 132 (2020) 116060. 中科院一区
[21] Liang Zhang; Yu Sun; Xiongyan Liang; Yuying Yang; Xianmei Meng; Qi Zhang; Peiwu Li; Yu Zhou. Cysteamine triggered “turn-on” fluorescence sensor for detection of fumonisin B1, B2 and B3, Food Chem., 327 (2020) 127058. 中科院一区
[22] Hualin Yang; Qi Zhang; Xiaolei Liu; Yuying Yang; Yong Yang; Mingyuan Liu; Peiwu Li; Yu Zhou. Antibody-biotin-streptavidin-HRP sensor for rapid and ultra-sensitive detection of fumonisins. Food Chem., 316 (2020) 126356. 中科院一区
[23] Junxiang Zhang, Die Xu, Zhenzhen Luo, Yanan Zhao, Xiaolong Zheng, Hualin Yang, Yu Zhou. Gold nanoparticle-mediated fluorescence immunoassay for rapid and sensitive detection of Ochratoxin A. Spectrochim. Acta Part A, 304 (2024) 123312. 中科院二区
[24] Xiaolong Zheng, Linlin Sun, Yanan Zhao, Hualin Yang, Yuanhua Zhu, Junxiang Zhang, Die Xu, Xingping Zhang, Yu Zhou. A fluorescence and colorimetric dual-mode immunoassay for detection of ochratoxin a based on cerium nanoparticles. Microchem. J., 201 (2024) 110419.中科院二区
[25] Yu Zhou, Yansong Li, Xiaoqian Tang, Hui Li, Qi Zhang, Ki Soo Park, Peiwu Li. A dual-signal output plasmonic sensor based on glucose oxidase-triggered etching of triangular silver nanoprism for sensitive detection of fumonisins. Microchem. J., 196 (2024) 109713. 中科院二区
[26] Linlin Sun, Xiaolong Zheng, Hualin Yang, Yuanhua Zhu, Junxiang Zhang, Xingping Zhang, Yu Zhou. A ratiometric fluorescence immunoassay based on Ce4+ oxidized o-phthalylenediamine and polyvinylpyrrolidone protected copper nanoclusters for the detection of aflatoxin B1. Microchem. J., 206 (2024) 111427. 中科院二区
[27] Xiaolong Zheng, Yanan Zhao, Yan Zhang, Yuanhua Zhu, Junxiang Zhang, Die Xu, Hualin Yang, Yu Zhou. Alkaline phosphatase triggered gold nanoclusters turn-on fluorescence immunoassay for detection of Ochratoxin A. Spectrochim. Acta Part A, 304 (2024) 123317. 中科院二区
[28] Yuanhua Zhu, Yanan Zhao, Hualin Yang, Jing Ma, Xiaolong Zheng, Junxiang Zhang, Die Xu, Xingping Zhang, Yu Zhou. Dual-readout colorimetric immunoassay based on halogenated indophenol for rapid detection of aflatoxin B1.Microchem. J., 197 (2024) 109741. 中科院二区
[29] Zhenzhen Luo, Junxiang Zhang, Jing Ma, Die Xu, Yanan Zhao, Yuanhua Zhu, Hualin Yang, Yu Zhou. Fluorescence and absorbance dual-mode immunoassay for detection of Ochratoxin A based on 2-aminoterephthalic acid and p-nitrophenol. J. Food Compos. Anal., 125 (2024) 105784. 中科院二区
[30] Shixiang Wu, Yanan Zhao, Yao Xiao, Liyuan Ma, Qi Zhang, Peiwu Li, Hualin Yang, Yu Zhou. Dual-readout immunoassay based on IFE and p-phenylenediamine for detection of zearalenone. J. Food Compos. Anal., 132 (2024) 106311. 中科院二区
[31] Guohao Zhang, Xingping Zhang, Qian Zhang, Wang Chen, Shixiang Wu, Hualin Yang, Yu Zhou. MnO2 nanosheets-triggered oxVB1 fluorescence immunoassay for detection zearalenone. Spectrochim. Acta Part A, 286 (2023) 121954. 中科院二区
[32] Qian Zhang, Xingping Zhang, Guohao Zhang, Wang Chen, Shixiang Wu, Hualin Yang, Yu Zhou. Multicolor immunosensor for detection of zearalenone based on etching Au NBPs mediated by HRP. J. Food Compos. Anal., 115 (2023) 105014. 中科院二区
[33] Huajuan Fang, Xingping Zhang, Liyuan Ma, Yao Xiao, Hualin Yang, Yu Zhou. Fluorescence detection of glyphosate based on G-quadruplex and porphyrin metalation. J. Food Compos. Anal., 116 (2023) 105074. 中科院二区
[34] Liyuan Ma, Xingping Zhang, Yu Peng, Wang Chen, Yao Xiao, Huajuan Fang, Hualin Yang, Yu Zhou. Based on intervening PCR for detection of alkaline phosphatase and zearalenone. Microchem. J., 186 (2023) 108314. 中科院二区
[35] Yu Peng; Mingming Xu; Yushuang Guo; Hualin Yang; Yu Zhou. A novel signal amplification biosensor for detection of Cd2+ based on asymmetric PCR. Spectrochim. Acta Part A, 271 (2022) 120885. 中科院二区
[36] Yu Peng; Mingming Xu; Hualin Yang; Yu Zhou. A double signal amplification strategy for sensitive detection of Hg2+ based on exonuclease III and PCR. Spectrochim. Acta Part A, 271 (2022) 120957. 中科院二区
[37] Huajuan Fang; Xingping Zhang; Dongxu Gao; Yao Xiao; Liyuan Ma; Hualin Yang; Yu Zhou. Fluorescence determination of glyphosate based on a DNA‑templated copper nanoparticle biosensor. Microchim. Acta (2022) 189:158. 中科院二区
[38] Yao Xiao, Xingping Zhang, Liyuan Ma, Huajuan Fang, Hualin Yang, Yu Zhou. Fluorescence and absorbance dual-mode immunoassay for detecting Ochratoxin A. Spectrochim. Acta Part A, 279 (2022) 121440. 中科院二区
[39] Xiaoli Yin; Yun-Qing Liu; Hui-Wen Gu; Qi Zhang; Zhao-Wei Zhang; Hui Li; Pei-Wu Li; Yu Zhou. Multicolor enzyme-linked immunosorbent assay sensor for the sensitive detection of organophosphorus pesticides based on TMB2+-mediated etching of gold nanorods. Microchem. J., 168 (2021) 106411. 中科院二区
[40] Ning Xu; Yan Liu; Yansong Li; Bin Tang; Xiongyan Liang; Yuying Yang; Mingyuan Liu; Xiaolei Liu; Yu Zhou. Rapid quantum dot nanobead-mAb probe-based immunochromatographic assay for antibody monitoring of trichinella spiralis infection. Int. J. Nanomed., 2021, 16 2477–2486. 中科院二区
[41] Hualin Yang; Yu Peng; Mingming Xu; Shuxia Xu; Yu Zhou. Development of DNA biosensors based on DNAzymes and nucleases. Crit. Rev. Anal. Chem., 2021, 53 (1): 161-176. 中科院二区
[42] Seokhwan Kim, Jinjoo Han, Heeseok Chung, Yong-Keun Choi, Ayemeh Bagheri Hashkavay, Yu Zhou, and Ki Soo Park. Pyrophosphate-enhanced oxidase activity of cerium oxide nanoparticles for colorimetric detection of nucleic acids. Sensors, 2021, 21 (22): 7567. 中科院二区
[43] Yonghong Zha; Xiaolei Liu; Pan Hu; Shiying Lu; Honglin Ren; Zengshan Liu; Xiongyan Liang; Yuying Yang; Yansong Li; Yu Zhou. Alkaline phosphatase–triggered immunoassay based on fluorogenic reaction for sensitive detection of acetochlor, metolachlor, and propisochlor. Food Anal. Method, 2020, (13): 1008–1016. 中科院二区
[44] Zhaozhao Si; Yansong Li; Shujuan han; Pan Hu; Shiying Lu; Honglin Ren; Baoling zhao; Xiongyan Liang; Yuying Yang; Fang wang; Yu Zhou. Gold nanorods-based multicolor immunosensor for visual detection of enterovirus 71 infection. Microchim. Acta (2020) 187:556. 中科院二区
[45] Yu Sun; Liang Zhang; Xianmei Meng; Xiaoli Yin; Yan Zhang; Jing Ma; Liangxiao Zhang; Ki Soo Park; Yu Zhou. A double-nanoprobe based immunoassay for rapid and sensitive detection of phenanthrene and its homolog. Microchem. J., 158 (2020) 105169. 中科院二区
[46] Hualin Yang; Wentao Xu; Xiongyan Liang; Yuying Yang; Yu Zhou. Carbon nanotubes in electrochemical, colorimetric and fluorimetric immunosensors and immunoassays: a review. Microch. Acta (2020) 187:206. 中科院二区
代表课题：
主持科研项目12项（其中国家自然科学基金面上项目6项）
1. 国家自然科学基金委员会，面上项目，32272411，基于SiO2纳米探针和贵金属纳米粒子局域表面等离子共振（LSPR）双重信号增敏的真菌毒素高灵敏免疫检测研究，2023-01至2026-12。
2. 国家自然科学基金委员会，面上项目，31871888，基于磁纳米微球和金纳米粒子双探针介导的有机磷农药（OPs）检测技术研究，2019-01至2022-12。
3. 国家自然科学基金委员会，面上项目，61571208，纳米金粒子介导的复合探针的设计合成及其在多环芳烃分析检测中的应用研究，2016-01至2019-12。
4. 国家自然科学基金委员会，面上项目，61171022，基于多价免疫生物传感器的原料乳中多种蛋白高通量检测新方法研究，2012-01至2015-12。
5. 国家自然科学基金委员会，面上项目，60971011，基于重组抗体的水环境中痕量重金属高通量检测技术研究，2010-01至2012-12。
6. 国家自然科学基金委员会，面上项目，30771657，以广谱单链抗体（ScFv）为探针筛检水环境及水产品中中毒性藻毒素，2008-01至2010-12。
7. 科技部重点研发计划项目，2017YFD0501302，畜禽重要人兽共患寄生虫病源头防控与阻断技（任务主持），2017-01至2020-12。
8. 科技部重点研发计划项目，2018YFC1602505，食品中生物毒素特异性增敏检测与非靶向确证技术研发（任务主持），2019-01至2021-12。
